For those of you who want to see how such fear mongering can lead to a decline in the use of effective treatment and therefore an increase in violent behavior that in fact leads to suicide and tragic death, we now present one Graham's typical statements on SSRI's
"With the SSRIs [Selective Serotonin Re-Uptake Inhibitors, the class of antidepressants including Prozac and Paxil], I think FDA pulled a fast one on the American people. Because they said, ï¿½we are using our most powerful labeling, our most powerful medicine: weï¿½re putting a black box around it.ï¿½ But it doesnï¿½t change physician behavior. People are as unsafe after the labeling goes into effect as they were before.
With the SSRI labeling, people are actually more deceived. Because the labeling says that the risk of suicidal thoughts and behavior in children is 1-2 percent. But FDAï¿½s own senior managers admitted at an open public advisory committee meeting that our clinical trials donï¿½t capture suicidal thoughts and behavior. So what we know about it is what has been voluntarily reported. There are lots more out there, we just didnï¿½t measure them. They have evidence from an NIH clinical trial that the risk is more like 8 percent. "
Members of Congress and senior officials of the FDA should be ashamed of themselves for giving Graham the chance to not only rant on about Vioxx and SSRIs but to make the same claims about Ketek and drugs for schizophrenia.