Steven E. Nissen, M.D., and Kathy Wolski, M.P.H. signals a new low for both the NEJM and Nissen who's campaign to be FDA commissioner in a Democrat administration makes him look craven and small. http://www.nejm.org
The article proves no direct causal association. As the authors admit "these findings are based on limited access to trial results from publicly available sources, not on patient-level source data." Which means they cannot control for previous risks of heart disease or prior events.
Worse, the authors ignore the extensive literature demonstrating an association between diabetes and death from heart problems. Here's one article it failed to mention.
Diabetes mellitus: the major risk factor in unstable coronary artery disease even after consideration of the extent of coronary artery disease and benefits of revascularization.
Am Coll Cardiol. 2004 Feb 18;43(4):585-91.
Nissen has trawled for trouble before in the area of drugs for ADHD where he was rebuked by people who know better about the medicines benefit/risk profile. Here, he just did some data dredging of the worst sort and then even failed to cover his rear by citing literature about the link between diabetes and heart disease.
We know the NEJM is no longer a credible source of objective information on medicine. The question regarding Nissen is: Is he a real doctor or just playing one in the media?